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“Our objective is to comprehend woman reproductive growing older, and why fertility quickly declines commencing from the mid-30s,” suggests Satoshi Namekawa, a professor of Microbiology and Molecular Genetics, in whose lab Munakata works.
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Utilizing the GCRLE grant, Munakata and Namekawa will search extra closely at how oocytes are genomically primed and stored for afterwards use. They will examine the function of the chromatin remodeler in oocyte survival and fertility.
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This protein might “create and sustain the chromatin point out,” suggests Namekawa — trying to keep the spools set up along with the oocytes genetically primed because the mouse matures.
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